Article
Particle-mediated gene transfer of PDGF isoforms promotes wound repair.
The Journal of investigative dermatology - 1 Mar 1999
Eming S A, Whitsitt J S, He L, Krieg T, Morgan J R, Davidson J M
Abstract excerpt
Several techniques for cutaneous gene transfer have been investigated for either in vitro or in vivo applications. In the present study, we investigated whether the direct delivery of platelet-derived growth factor cDNA into skin results in improvement in tissue repair. Cutaneous transfections were carried out in rats using a particle-bombardment device (Accell). As revealed by reverse transcriptase-polymerase...
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