Article
Engineering of tooth-supporting structures by delivery of PDGF gene therapy vectors.
Molecular therapy : the journal of the American Society of Gene Therapy - 1 Apr 2004
Jin Qiming, Anusaksathien Orasa, Webb Sarah A, Printz Marie A, Giannobile William V
Abstract excerpt
Platelet-derived growth factor (PDGF) exerts potent effects on wound healing including the regeneration of tooth-supporting structures. Limitations of topical protein delivery to periodontal osseous defects include transient biological activity and the bioavailability of PDGF at the wound site. T...
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