Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Trinucleotide repeat analysis of Huntington's disease gene in Singapore.

Annals of the Academy of Medicine, Singapore - 1 Mar 2001

Law H Y, Ng I S, Yoon C S, Zhao Y, Wong M C

Abstract excerpt

INTRODUCTION: Huntington's disease (HD) is an inherited neurodegenerative disorder characterised by chorea and progressive dementia. The mutation causing the disease has been identified as an unstable expansion of a trinucleotide (CAG)n. We have assessed the (CAG)n repeats in the patients and controls in our population. MATERIALS AND METHODS: Polymerase chain reactions (PCRs) for the repeat region were carried...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Aged, 80 and over
Share to Child

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Electrophoresis, Agar Gel

Share to Huntington Disease

Share to Polymerase Chain Reaction

Share to Singapore

Share to Trinucleotide Repeats

Source

Identifiers

PMID: 11379408

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Trinucleotide repeat analysis of Huntington's disease gene in Singapore.PMID 11379408Read ↗

A worldwide study of the Huntington's disease mutation. The sensitivity and specificity of measuring CAG repeats.Semantic proximity Read ↗

Challenges facing genetic diagnostics of Huntington's disease: an update.Semantic proximity Read ↗

A study of the Huntington's disease associated trinucleotide repeat in the Scottish population.Semantic proximity Read ↗

Analysis of HTT CAG repeat expansion among healthy individuals and patients with chorea in Korea.Semantic proximity Read ↗

[Genetic diagnosis of Huntington disease].Semantic proximity Read ↗

A study on Huntington's disease associated trinucleotide repeat within the Chinese population.Semantic proximity Read ↗

Simple procedure for automatic detection of unstable alleles in the myotonic dystrophy and Huntington's disease loci.Semantic proximity Read ↗

Large normal and reduced penetrance alleles in Huntington disease: instability in families and frequency at the laboratory, at the clinic and in the population.Semantic proximity Read ↗

Single sperm analysis of the trinucleotide repeats in the Huntington's disease gene: quantification of the mutation frequency spectrum.Semantic proximity Read ↗

Huntington disease: DNA analysis in Brazilian population.Semantic proximity Read ↗

Analysis of the huntingtin gene reveals a trinucleotide-length polymorphism in the region of the gene that contains two CCG-rich stretches and a correlation between decreased age of onset of Huntington's disease and CAG repeat number.Semantic proximity Read ↗

Trinucleotide (CAG) repeat expansion in chromosomes of Spanish patients with Huntington's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.