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[Genetic diagnosis of Huntington disease].

Yi chuan = Hereditas - 1 Nov 2005

Mo Ya-Qin, Li Lu-Yun, Lu Guang-Xiu

Abstract excerpt

We report here a simple and effective method to assess the CAG repeat size of HD gene for gene diagnosis of Huntington disease. Genomic DNA sequences in polymorphic CAG repeat HD gene was amplified by PCR with TaKaRa LA Taq DNA polymerase and GC buffer. To distinguish normal alleles from HD alleles, DNA fragments of affected alleles were recovered as templates for secondary PCR. The secondary PCR products were...

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PMID: 16378928

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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