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Article

Enhanced axonal growth from fetal human bcl-2 transgenic mouse dopamine neurons transplanted to the adult rat striatum.

Neuroscience - 1 Jan 2001

Holm K H, Cicchetti F, Bjorklund L, Boonman Z, Tandon P, Costantini L C, Deacon T W, Huang X, Chen D F, Isacson O

Abstract excerpt

Embryonic neurons transplanted to the adult CNS extend axons only for a developmentally defined period. There are certain intercellular factors that control the axonal extension, one of which may be the expression of the bcl-2 protein. In this study, rats with complete striatal dopamine fiber denervation received embryonic day 14 mouse ventral mesencephalon cells overexpressing human bcl-2 or control wild-type...

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Source

Identifiers

PMID: 11377843
DOI: 10.1016/s0306-4522(01)00098-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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