Article
Myelomastocytic overlap syndromes: biology, criteria, and relationship to mastocytosis.
Leukemia research - 1 Jul 2001
Valent P, Sperr W R, Samorapoompichit P, Geissler K, Lechner K, Horny H P, Bennett J M
Abstract excerpt
Although mast cells (MC) appear to be myeloid cells, MC lineage involvement in myelogenous malignancies has been described only rarely. Based on clonal evolution, biology of afflicted cells, and disease criteria, three major groups of patients have been recognized: The first meets criteria for both diagnoses 'systemic mastocytosis' and 'associated hematologic clonal non-mast cell lineage disease (AHNMD)'. In such...
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