Article
Mutational analysis of the feline immunodeficiency virus matrix protein.
Virus research - 1 Jul 2001
Manrique M L, Celma C C, González S A, Affranchino J L
Abstract excerpt
To study the process of feline immunodeficiency virus (FIV) assembly, we examined the suitability of the vaccinia vector system to reproduce FIV particle formation. To this end, we constructed a recombinant vaccinia virus carrying the FIV gag gene. Biochemical and electron microscopy analyses of cells infected with this recombinant virus showed that the FIV Gag polyprotein self-assembled into lentivirus-like...
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