Article
S-nitrosoglutathione increases cystic fibrosis transmembrane regulator maturation.
Biochemical and biophysical research communications - 1 Jun 2001
Zaman K, McPherson M, Vaughan J, Hunt J, Mendes F, Gaston B, Palmer L A
Abstract excerpt
Endogenous S-nitrosoglutathione (GSNO) is known to increase the expression of certain proteins at concentrations present in the normal human airway. We hypothesized that GSNO would increase expression and maturation of the cystic fibrosis transmembrane conductance regulator (CFTR). Cells expressing DeltaF508 and wild type CFTR were exposed to GSNO and analyzed for expression and maturation by Western blot...
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