Article
Evidence for the non-quasispecies evolution of RNA viruses [corrected].
Molecular biology and evolution - 1 Jun 2001
Jenkins G M, Worobey M, Woelk C H, Holmes E C
Abstract excerpt
The quasispecies model of RNA virus evolution differs from those formulated in conventional population genetics in that neutral mutations do not lead to genetic drift of the population, and natural selection acts on the mutant distribution as a whole rather than on individual variants. By computer simulation, we show that this model could be inappropriate for many RNA viruses because the neutral sequence space...
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