Article
Detection of human apolipoprotein E genotypes by DNA biosensors coupled with PCR.
Clinica chimica acta; international journal of clinical chemistry - 1 May 2001
Marrazza G, Tombelli S, Mascini M, Manzoni A
Abstract excerpt
Apolipoprotein E (apoE) is an important constituent of several plasma lipoproteins and has been associated with the risk of developing cardiovascular diseases and in familiar type III hyperlipoproteinemia. We developed new procedures for the detection of apolipoprotein E polymorphism in human blood based on coupling DNA electrochemical or piezoelectric sensors with polymerase chain reaction (PCR). The...
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