Article
Molecular basis of rifampin and isoniazid resistance in Mycobacterium bovis strains isolated in Sardinia, Italy.
Antimicrobial agents and chemotherapy - 1 Jun 2001
Sechi L A, Zanetti S, Sanguinetti M, Molicotti P, Romano L, Leori G, Delogu G, Boccia S, La Sorda M, Fadda G
Abstract excerpt
Fourteen of 22 (68%) Mycobacterium bovis strains isolated from cattle in Sardinia were found to be resistant to rifampin and isoniazid. Analysis of the rpoB and the katG, oxyR-ahpC, and inhA gene regions of these strains was performed in order to investigate the molecular basis of rifampin and isoniazid resistance, respectively. The most frequent mutation, encountered in 6 of 10 strains (60%), was in the rpoB...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.