Article
Additional evidence that genetic variation of MAO-A gene supports a gender subtype in obsessive-compulsive disorder.
American journal of medical genetics - 8 Apr 2001
Camarena B, Rinetti G, Cruz C, Gómez A, de La Fuente J R, Nicolini H
Abstract excerpt
Studies have recently reported a sexually dimorphic association between obsessive-compulsive disorder (OCD) and a polymorphism related with variations in MAO-A activity. These observations suggest the possibility of gender differences in genetic susceptibility for OCD. We thus reexamined the MAO-A/EcoRV polymorphism in a sample of 122 OCD patients and 124 healthy subjects. An excess of allele 1 in OCD females...
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