Article
UV induces nucleolar translocation of ING1 through two distinct nucleolar targeting sequences.
Nucleic acids research - 15 May 2001
Scott M, Boisvert F M, Vieyra D, Johnston R N, Bazett-Jones D P, Riabowol K
Abstract excerpt
The ING1 candidate tumor suppressor is downregulated in a variety of primary tumors and established cancer cell lines. Blocking its expression experimentally promotes unregulated growth in vitro and in vivo, using cell and animal models. Alternative splicing products encode proteins that localize...
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