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Article

The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation.

Cell - 4 May 2001

Tapon N, Ito N, Dickson B J, Treisman J E, Hariharan I K

Abstract excerpt

The inherited human disease tuberous sclerosis, characterized by hamartomatous tumors, results from mutations in either TSC1 or TSC2. We have characterized mutations in the Drosophila Tsc1 and Tsc2/gigas genes. Inactivating mutations in either gene cause an identical phenotype characterized by en...

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Source

Identifiers

PMID: 11348591
DOI: 10.1016/s0092-8674(01)00332-4

Genes

TSC1
TSC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-11348591-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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