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Article

The tuberous sclerosis complex genes in tumor development.

Cancer investigation - 1 Jan 2004

Mak Baldwin C, Yeung Raymond S

Abstract excerpt

The study of hereditary tumor syndromes has laid a solid foundation toward understanding the genetic basis of cancer. One of the latest examples comes from the study of tuberous sclerosis complex (TSC). As a member of the phakomatoses, TSC is characterized by the appearance of benign tumors, most notably in the central nervous system, kidney, heart, lung, and skin. While classically described as "hamartomas," the...

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Source

Identifiers

PMID: 15565817
DOI: 10.1081/cnv-200027144

Genes

TSC1
TSC2
APC
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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