Article
Concordance for type 1 diabetes in identical twins is affected by insulin genotype.
Diabetes care - 1 May 2001
Metcalfe K A, Hitman G A, Rowe R E, Hawa M, Huang X, Stewart T, Leslie R D
Abstract excerpt
OBJECTIVE: Monozygotic twins are usually discordant (only one twin affected) for type 1 diabetes. Discordance for disease between such twins implies a role for nongenetically determined factors but could also be influenced by a decreased load of diabetes susceptibility genes. The aim of this study was to determine whether two susceptibility genes were less prevalent in discordant twins compared with concordant...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.