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Article

Location of the Epitope for 7D5, a Monoclonal Antibody Raised against Human Flavocytochrome b558, to the Extracellular Peptide Portion of Primate gp91phox

1 Mar 2001

Abstract excerpt

Flavocytochrome b558 is the membrane component of the phagocyte NADPH oxidase, and is a heterodimer composed of gp91phox and p22phox subunits. Human flavocytochrome b558 is recognized by monoclonal antibody 7D5 at an unidentified extracellular domain, although our previous study suggested it might recognize p22phox. 7D5 has proven useful in rapid screening of individuals for X-linked chronic granulomatous disease...

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Identifiers

PMID: 11345535
DOI: 10.1111/j.1348-0421.2001.tb02614.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Location of the Epitope for 7D5, a Monoclonal Antibody Raised against Human Flavocytochrome b558, to the Extracellular Peptide Portion of Primate gp91phoxPMID 11345535Read ↗

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Characterization of a mutation in the Phox homology domain of the NADPH oxidase component p40phox identifies a mechanism for negative regulation of superoxide production.Semantic proximity Read ↗

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