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Article

Expression of Human MUC1 During Early Pregnancy in the Human MUC1 Transgenic Mouse Model1

15 Aug 2009

Abstract excerpt

Embryo implantation involves direct interaction of the blastocyst with the luminal epithelium of the receptive uterus. MUC1, a transmembrane mucin expressed at the apical surface of uterine epithelia, acts as a barrier to microbial infection and enzymatic attack. Loss of MUC1 is believed to be a prerequisite for a functionally receptive uterus across many species. Human and murine MUC1 regulation by steroid...

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PMID: 19684334
DOI: 10.1095/biolreprod.109.079418

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