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Article

The TprK protein of Treponema pallidum is periplasmic and is not a target of opsonic antibody or protective immunity.

The Journal of experimental medicine - 7 May 2001

Hazlett K R, Sellati T J, Nguyen T T, Cox D L, Clawson M L, Caimano M J, Radolf J D

Abstract excerpt

The finding that Treponema pallidum, the syphilis spirochete, contains 12 orthologs of the Treponema denticola outer membrane major sheath protein has engendered speculation that members of this T. pallidum repeat (Tpr) family may be similarly surface exposed. In this regard, the TprK protein was reported to be a target of opsonic antibody and protective immunity and subject to immunologically driven sequence...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11342586
DOI: 10.1084/jem.193.9.1015
PMCID: PMC2193430

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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