Article
Primary mouse myoblast purification, characterization, and transplantation for cell-mediated gene therapy.
The Journal of cell biology - 1 Jun 1994
Rando T A, Blau H M
Abstract excerpt
The transplantation of cultured myoblasts into mature skeletal muscle is the basis for a new therapeutic approach to muscle and non-muscle diseases: myoblast-mediated gene therapy. The success of myoblast transplantation for correction of intrinsic muscle defects depends on the fusion of implante...
Topics
- Animals
- Cell Differentiation
- Cell Division
- Cell Fusion
- Clone Cells
- Culture Techniques
- Genetic Therapy
- Immunosuppression Therapy
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Mice, Nude
- Muscles
- Neoplasms, Muscle Tissue
- Phenotype
- Stem Cells
- Tissue Transplantation