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Article

PTHrP rescues ATDC5 cells from apoptosis induced by FGF receptor 3 mutation.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Aug 2003

Yamanaka Yoshitaka, Tanaka Hiroyuki, Koike Mio, Nishimura Riko, Seino Yoshiki

Abstract excerpt

UNLABELLED: An activation mutation in the FGFR3 gene causes ACH. The effects of the FGFR3 mutants on apoptosis were analyzed in a chondrogenic cell line. ACH chondrocytes exhibited marked apoptotic with downregulation of PTHrP expression. Rescue of these cells by PTHrP replacement implies a poten...

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Source

Identifiers

PMID: 12929929
DOI: 10.1359/jbmr.2003.18.8.1395

Genes

FGFR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12929929-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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PTHrP rescues ATDC5 cells from apoptosis induced by FGF receptor 3 mutation.PMID 12929929Read ↗

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