Article
Relevance of potential endocytosis motifs in Cedar virus glycoprotein G for its biological activity.
Journal of virology - 19 May 2026
Burrer Céline, Hund Inga, Rüdiger Carolin, Reiche Sven, Groschup Martin H, Tews Birke A, Ushakov Dmitry S, Fischer Kerstin, Diederich Sandra
Abstract excerpt
The glycoprotein (G) and fusion protein (F) of henipaviruses play crucial roles in receptor binding and entry into host cells, also enabling virus spread from cell to cell without the release of infectious particles. For Cedar virus (CedV), the proteolytic activation of the F protein precursor into F1 and F2-and thus, its biological activity-depends on clathrin-mediated endocytosis driven by classical endocytosis...
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