Article
PCR-RFLP genotyping assay for the Bcl I polymorphism of the beta-fibrinogen gene.
Genetic testing - 1 Jan 2001
Sell S M, Song C, Booyse F M
Abstract excerpt
Polymorphisms of the beta-fibrinogen gene have been shown to affect plasma fibrinogen levels and risk of coronary artery disease (CAD). We were interested in developing an automated, PCR-based genotyping assay for the purpose of exploring relationships between CAD and CAD-associated aortic stiffness and the Bcl I allele of the beta-fibrinogen gene. We have developed a rapid PCR-RFLP assay for the Bcl I...
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