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Article

Mitochondrial DNA content affects the fertilizability of human oocytes

1 May 2001

Abstract excerpt

Mitochondrial DNA content varies considerably in oocytes, even when collected from the same patient. In the present study, real-time quantitative polymerase chain reaction analysis of 113 unfertilized oocytes obtained from 43 patients revealed an average of 193,000 (range: 20,000 to 598,000) mitochondrial genomes per cell. We compared several groups of oocytes to investigate the relationship between mitochondrial...

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PMID: 11331664
DOI: 10.1093/molehr/7.5.425

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