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Streptococcus iniae beta-hemolysin streptolysin S is a virulence factor in fish infection.

Diseases of aquatic organisms - 7 Jun 2007

Locke Jeffrey B, Colvin Kelly M, Varki Nissi, Vicknair Mike R, Nizet Victor, Buchanan John T

Abstract excerpt

Streptococcus iniae is a leading pathogen of intensive aquaculture operations worldwide, although understanding of virulence mechanisms of this pathogen in fish is lacking. S. iniae possesses a homolog of streptolysin S (SLS), a secreted, pore-forming cytotoxin that is a proven virulence factor in the human pathogen S. pyogenes. Here we used allelic exchange mutagenesis of the structural gene for the S. iniae SLS...

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PMID: 17718161
DOI: 10.3354/dao076017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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