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Article

Modulatory effect of prostaglandins on human monocyte activation for killing of high‐ and low‐virulence strains of <i>Paracoccidioides brasiliensis</i>

1 Apr 2001

Abstract excerpt

The effect of indomethacin (Indo), a cyclo-oxygenase inhibitor, on the monocyte-mediated killing of a low- (Pb265) and a high- (Pb18) virulence strain of Paracoccidioides brasiliensis was examined. The Pb18 strain was not killed by either non-activated or interferon-gamma (IFN-gamma) -activated human monocytes but these cells did show fungicidal activity if pretreated with Indo. In contrast with IFN-gamma, tumour...

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Identifiers

PMID: 11328382
DOI: 10.1046/j.1365-2567.2001.01179.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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