Article
Virulence profile of ten Paracoccidioides brasiliensis isolates: association with morphologic and genetic patterns.
Revista do Instituto de Medicina Tropical de Sao Paulo - 1 Jan 2000
Kurokawa Cilmery S, Lopes Catalina R, Sugizaki Maria F, Kuramae Eiko E, Franco Marcello F, Peraçoli Maria T S
Abstract excerpt
Ten isolates of Paracoccidioides brasiliensis were examined for differences in virulence in outbred mice intravenously inoculated with the fungus, associated with mycelial morphology, and genetic patterns measured by random amplified polymorphic DNA (RAPD). Virulence was evaluated by viable yeast cell recovery from lungs and demonstration of histopathologic lesions in different organs. The results showed that the...
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