Article
Phenotypic and functional evaluations of peripheral blood monocytes from chronic-form paracoccidioidomycosis patients before and after treatment.
BMC infectious diseases - 16 Oct 2014
Venturini James, Cavalcante Ricardo Souza, Golim Márjorie de Assis, Marchetti Camila Martins, Azevedo Priscila Zacarias de, Amorim Bárbara Casella, Arruda Maria Sueli Parreira de, Mendes Rinaldo Poncio
Abstract excerpt
BACKGROUND: Paracoccidioidomycosis (PCM) is systemic mycosis caused by the thermal dimorphic fungus of genus Paracoccidioides, leading to either acute/subacute (AF) or chronic (CF) clinical forms. Numerous CF patients after treatment exhibit sequels, such as pulmonary and adrenal fibrosis. Monocytes are cells that are involved in the inflammatory response during active infection as well as in the fibrogenesis....
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