Article
p73beta, a variant of p73, enhances Wnt/beta-catenin signaling in Saos-2 cells.
Biochemical and biophysical research communications - 4 May 2001
Ueda Y, Hijikata M, Takagi S, Takada R, Takada S, Chiba T, Shimotohno K
Abstract excerpt
The Wnt/beta-catenin pathway and p53 are very common targets for genetic alterations in colorectal cancer, and relationships between them have been reported. Here, we describe the relation between Wnt/beta-catenin signaling and the p53-related gene p73. p73, but not p53, activated a promoter cont...
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