Article
Genomic instability: potential contributions to tumour and normal tissue response, and second tumours, after radiotherapy.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 May 2001
Hendry J H
Abstract excerpt
PURPOSE: Induced genomic instability generally refers to a type of damage which is transmissible down cell generations, and which results in a persistently enhanced frequency of de novo mutations, chromosomal abnormalities or lethality in a significant fraction of the descendant cell population. The potential contribution of induced genomic instability to tumour and normal tissue response, and second tumours,...
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