Article
The role of cyclins and cyclin dependent kinases in development and progression of hepatitis C virus-genotype 4-associated hepatitis and hepatocellular carcinoma.
Experimental and molecular pathology - 1 Oct 2011
Bahnassy Abeer A, Zekri Abdel-Rahman N, Loutfy Samah A, Mohamed Waleed S, Moneim Amrallah Abdel, Salem Salem E, Sheta Marwa M, Omar Ashraf, Al-Zawahry Heba
Abstract excerpt
UNLABELLED: Altered cell cycle regulatory genes expression contributes to HCV-associated liver disease. We sought to assess the role of cyclins and cyclin dependent kinases (CDKs) in HCV-associated CH and HCC. Aberrant expression of cyclins A, E, D1, CDK2 and CDK4 was assessed by immunohistochemi...
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