Article
Functional polymorphism within the promotor of the serotonin transporter gene is associated with severe hyperkinetic disorders.
Molecular psychiatry - 1 Mar 2001
Seeger G, Schloss P, Schmidt M H
Abstract excerpt
In children and adolescents, hyperkinetic disorder (HD) with conduct disorder (CD) and without CD and attention-deficit/hyperactivity disorder (ADHD) is known to be comorbid with psychiatric disorders (anxiety, depression, aggression), some of which are related to disturbed serotonergic neurotransmission. The efficiency of serotonergic signalling relates to the concentration of the neurotransmitter in the...
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