Article
Overexpression of parathyroid hormone-related protein enhances apoptosis in the rat intestinal cell line, IEC-6.
Endocrinology - 1 May 2001
Ye Y, Wang C, Du P, Falzon M, Seitz P K, Cooper C W
Abstract excerpt
We used the rat intestinal cell line, IEC-6, to study potential effects of overexpression of PTH-related protein (PTHrP) on apoptosis. A clonal line of PTHrP-overexpressing cells was established by stably transfecting parental cells with PTHrP complementary DNA in a sense orientation (sense). A similarly transfected line stably, transfected with empty vector, served as control (vector). Immunoreactive PTHrP,...
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