Article
Apoptosis and bcl-2 expression as predictors of survival in radiation-treated non-small-cell lung cancer.
International journal of radiation oncology, biology, physics - 1 May 2001
Hwang J H, Lim S C, Kim Y C, Park K O, Ahn S J, Chung W K
Abstract excerpt
OBJECTIVES: We assessed the role of apoptosis and the expression of bcl-2, p53, and c-myc oncoproteins in pretreatment histologic specimens as a predictor of response to radiation therapy and survival in non-small-cell lung cancer (NSCLC) patients. METHODS: Pretreatment biopsy specimens of 68 patients with NSCLC (62 squamous cell carcinoma, 6 adenocarcinoma) were stained with hematoxylin and eosin. From 5...
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