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Radiation induced apoptosis and initial DNA damage are inversely related in locally advanced breast cancer patients

24 Sept 2010

Abstract excerpt

BACKGROUND: DNA-damage assays, quantifying the initial number of DNA double-strand breaks induced by radiation, have been proposed as a predictive test for radiation-induced toxicity. Determination of radiation-induced apoptosis in peripheral blood lymphocytes by flow cytometry analysis has also been proposed as an approach for predicting normal tissue responses following radiotherapy. The aim of the present...

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Share to Carcinogens and Genotoxicity Assessment
Share to Cell death mechanisms and regulation
Share to Effects of Radiation Exposure

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PMID: 20868468
DOI: 10.1186/1748-717x-5-85

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