Article
A site in the complement receptor 2 (CR2/CD21) silencer is necessary for lineage specific transcriptional regulation.
International immunology - 1 May 2001
Makar K W, Ulgiati D, Hagman J, Holers V M
Abstract excerpt
Expression of human complement receptor type 2 (CR2/CD21) is primarily restricted to mature B cells and follicular dendritic cells. We previously described an intronic transcriptional silencer that controls the appropriate B cell-specific and developmentally restricted expression of human CR2/CD21 in both stably transfected cell lines and transgenic mice. Here we report the identification of a nucleotide sequence...
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