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Article

Characterizing Class I WW domains defines key specificity determinants and generates mutant domains with novel specificities.

Chemistry & biology - 1 Mar 2001

Kasanov J, Pirozzi G, Uveges A J, Kay B K

Abstract excerpt

INTRODUCTION: WW domains are small protein interaction modules found in a wide range of eukaryotic signaling and structural proteins. Five classes of WW domains have been annotated to date, where each class is largely defined by the type of peptide ligand selected, rather than by similarities wit...

Read the complete abstract on PubMed

Topics

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Share to Conserved Sequence
Share to Peptide Library
Share to Protein Structure, Tertiary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Repetitive Sequences, Amino Acid

Share to Saccharomyces cerevisiae

Share to Sequence Alignment

Share to Substrate Specificity

Share to Tryptophan

Source

Identifiers

PMID: 11306348
DOI: 10.1016/s1074-5521(01)00005-9

Genes

WWP1
WWP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11306348-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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