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Article

Anti-DNA antibody subpopulations and lupus nephritis.

Autoimmunity reviews - 1 Feb 2004

Rekvig O P, Kalaaji M, Nossent H

Abstract excerpt

As a consequence of increased insight into the cellular and molecular mechanisms responsible for induction of B cell and T cell autoimmunity to DNA and nucleosomes, there is an obvious need to reconsider the dogma stating that anti-dsDNA antibodies serve as marker antibodies for SLE and also that anti-dsDNA antibodies per se are responsible for the initiation of lupus nephritis. Given that the potential to...

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PMID: 15003181
DOI: 10.1016/S1568-9972(03)00081-8

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