Article
Molecular biology and clinical implication of hepatitis C virus.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 May 2004
Lyra A C, Fan X, Di Bisceglie A M
Abstract excerpt
Hepatitis C virus (HCV) was first described in 1989 as the putative viral agent of non-A non-B hepatitis. It is a member of the Flaviviridae family and has been recognized as the major causative agent of chronic liver disease, including chronic active hepatitis, cirrhosis and hepatocellular carcinoma. HCV is a positive RNA virus with a genome containing approximately 9500 nucleotides. It has an open reading frame...
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