Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of mouse Dach2, a homologue of Drosophila dachshund.

Mechanisms of development - 1 Apr 2001

Davis R J, Shen W, Sandler Y I, Heanue T A, Mardon G

Abstract excerpt

The Drosophila genes eyeless, eyes absent, sine oculis and dachshund cooperate as components of a network to control retinal determination. Vertebrate homologues of these genes have been identified and implicated in the control of cell fate. We present the cloning and characterization of mouse Dach2, a homologue of dachshund. In situ hybridization studies demonstrate Dach2 expression in embryonic nervous tissues,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to PAX3 Transcription Factor
Share to Nervous System
Share to Paired Box Transcription Factors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to PAX6 Transcription Factor

Share to RNA, Long Noncoding

Share to RNA, Untranslated

Share to Tissue Distribution

Share to X Chromosome

Source

Identifiers

PMID: 11287190
DOI: 10.1016/s0925-4773(01)00307-0

Genes

DACH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of mouse Dach2, a homologue of Drosophila dachshund.PMID 11287190Read ↗

Mouse Dach2 mutants do not exhibit gross defects in eye development or brain function.Semantic proximity Read ↗

Mouse Dac, a novel nuclear factor with homology to Drosophila dachshund shows a dynamic expression in the neural crest, the eye, the neocortex, and the limb bud.Semantic proximity Read ↗

DACH: genomic characterization, evaluation as a candidate for postaxial polydactyly type A2, and developmental expression pattern of the mouse homologue.Semantic proximity Read ↗

Mouse Dach1 and Dach2 are redundantly required for Müllerian duct developmentSemantic proximity Read ↗

Dach1 mutant mice bear no gross abnormalities in eye, limb, and brain development and exhibit postnatal lethality.Semantic proximity Read ↗

Structure-function analysis of the Drosophila retinal determination protein Dachshund.Semantic proximity Read ↗

EYA4, a novel vertebrate gene related to Drosophila eyes absent.Semantic proximity Read ↗

Dual regulation and redundant function of two eye-specific enhancers of the Drosophila retinal determination gene dachshund.Semantic proximity Read ↗

Targeted disruption of mouse Dach1 results in postnatal lethality.Semantic proximity Read ↗

DACH1 is a cell fate determination factor that inhibits cyclin D1 and breast tumor growth.Semantic proximity Read ↗

Characterization of mouse Dactylaplasia mutations: a model for human ectrodactyly SHFM3.Semantic proximity Read ↗

Ectopic eye development in Drosophila induced by directed dachshund expression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.