Article
Sex-specific viability effects of mutations in Drosophila melanogaster.
Evolution; international journal of organic evolution - 28 Oct 2024
Melde Robert H, Abraham JoHanna M, Ugolini Maryn R, Castle Madison P, Fjalstad Molly M, Blumstein Daniela M, Durski Sarah J, Sharp Nathaniel P
Abstract excerpt
In populations with separate sexes, genetic load due to deleterious mutations may be expressed differently in males and females. Evidence from insect models suggests that selection against mutations is stronger in males. This pattern will reduce deleterious allele frequencies at the expense of males, such that female mean fitness is greater than expected, preserving population persistence in the face of high...
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