Article
Detection of gene amplification in intraductal and infiltrating breast cancer by laser-assisted microdissection and quantitative real-time PCR.
Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2000
Glöckner S, Lehmann U, Wilke N, Kleeberger W, Länger F, Kreipe H
Abstract excerpt
Gene amplification is one essential mechanism leading to oncogene activation which is supposed to play a major role in the pathogenesis of invasive breast cancer. However, using standard methodologies the detection of gene amplifications has been limited especially in small-sized lesions, like pr...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
