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Article

Transduction of Liver Cells by Lentiviral Vectors: Analysis in Living Animals by Fluorescence Imaging

1 Mar 2001

Abstract excerpt

Viral vectors based on lentiviruses, such as the human immunodeficiency virus, are able to transduce a broad spectrum of nondividing cells in vivo. This ability of lentiviral vectors makes them an attractive vehicle for gene transfer into the liver. In order to determine the requirements for efficient lentiviral gene transfer, we used a fluorescence imaging system, which allows the detection of cells and tissues...

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Identifiers

PMID: 11273773
DOI: 10.1006/mthe.2001.0276

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