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Article

Efficient Gene Delivery and Targeted Expression to Hepatocytes <i>In Vivo</i> by Improved Lentiviral Vectors

20 Jan 2002

Abstract excerpt

Safe and efficient genetic modification of liver cells could enable new therapies for a variety of hepatic and systemic diseases. Lentiviral vectors are promising tools for in vivo gene delivery. Previous data suggested that recruitment into the cell cycle was required for transduction of hepatocytes in vivo. We developed an improved vector design that enhanced nuclear translocation in target cells and...

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Identifiers

PMID: 11812281
DOI: 10.1089/10430340252769770

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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