Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reduced intracellular survival of Helicobacter pylori vacA mutants in comparison with their wild-types indicates the role of VacA in pathogenesis.

FEMS immunology and medical microbiology - 1 Mar 2001

Petersen A M, Sørensen K, Blom J, Krogfelt K A

Abstract excerpt

The vacuolating cytotoxin VacA of Helicobacter pylori plays an important but yet unknown role in pathogenesis. We studied the impact of the vacuolating cytotoxin on H. pylori invasion of and survival within AGS cells (human gastric cell line derived from an antral adenocarcinoma). Isogenic vacA a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Bacterial Adhesion
Share to Bacterial Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Culture Media

Share to Genetic Complementation Test

Share to Gentamicins

Share to Helicobacter pylori

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 11267841
DOI: 10.1111/j.1574-695X.2001.tb01556.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11267841-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reduced intracellular survival of Helicobacter pylori vacA mutants in comparison with their wild-types indicates the role of VacA in pathogenesis.PMID 11267841Read ↗

Role of vacuolating cytotoxin A in Helicobacter pylori infection and its impact on gastric pathogenesis.Semantic proximity Read ↗

Remodeling the host environment: modulation of the gastric epithelium by the Helicobacter pylori vacuolating toxin (VacA)Semantic proximity Read ↗

Induction of gastric epithelial cell apoptosis by Helicobacter pylori vacuolating cytotoxin.Semantic proximity Read ↗

Effect of Helicobacter pylori on gastric epithelial cell migration and proliferation in vitro: role of VacA and CagA.Semantic proximity Read ↗

Pathological significance and molecular characterization of the vacuolating toxin gene of Helicobacter pyloriSemantic proximity Read ↗

Binding and internalization of the Helicobacter pylori vacuolating cytotoxin by epithelial cellsSemantic proximity Read ↗

Vacuolating cytotoxin A (VacA) - A multi-talented pore-forming toxin from Helicobacter pylori.Semantic proximity Read ↗

Natural diversity in the N terminus of the mature vacuolating cytotoxin of Helicobacter pylori determines cytotoxin activity.Semantic proximity Read ↗

Expression of CEACAM1 or CEACAM5 in AZ-521 cells restores the type IV secretion deficiency for translocation of CagA byHelicobacter pyloriSemantic proximity Read ↗

A Helicobacter pylori vacuolating toxin mutant that fails to oligomerize has a dominant negative phenotype.Semantic proximity Read ↗

Characterization of CagI in the cag pathogenicity island of Helicobacter pylori.Semantic proximity Read ↗

The <i>Helicobacter pylori</i>'s protein VacA has direct effects on the regulation of cell cycle and apoptosis in gastric epithelial cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.