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Article

Cloning, expression and genomic structure of human LMX1A, and variant screening in Pima Indians.

Gene - 15 May 2002

Thameem Farook, Wolford Johanna K, Wang Juehu, German Michael S, Bogardus Clifton, Prochazka Michal

Abstract excerpt

LIM-homeodomain containing protein LMX1A activates transcription of the insulin gene. The human LMX1A gene maps to 1q22-q23, a region identified as a putative type 2 diabetes mellitus (T2DM) locus in several different populations. We analyzed LMX1A as a positional and biological candidate gene for T2DM in the Pima Indians, in whom a linkage of T2DM to 1q21-q23 has been previously reported. In the present study,...

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Identifiers

PMID: 12062816
DOI: 10.1016/s0378-1119(02)00582-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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