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Initiation of HIV Reverse Transcription

18 Jan 2010

Abstract excerpt

Reverse transcription of retroviral genomes into double stranded DNA is a key event for viral replication. The very first stage of HIV reverse transcription, the initiation step, involves viral and cellular partners that are selectively packaged into the viral particle, leading to an RNA/protein complex with very specific structural and functional features, some of which being, in the case of HIV-1, linked to...

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PMID: 21994608
DOI: 10.3390/v2010213

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