Article
No association between IL-10 promoter gene polymorphism and heart failure or rejection following cardiac transplantation.
Tissue antigens - 1 Feb 2001
Bijlsma F J, Bruggink A H, Hartman M, Gmelig-Meyling F H, Tilanus M G, de Jonge N, de Weger R A
Abstract excerpt
Expression of interleukin (IL)-10 influences the frequency of rejection events after organ transplantation. Therefore, 70 heart transplant patients were genotyped for three single nucleotide polymorphisms and a microsatellite polymorphism in the promotor region of the IL-10 gene. The promoter region was amplified by polymerase chain reaction and genotyped by a colorometric oligo ligation assay and gene scan...
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