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Article

Responses to ultraviolet-B in cell lines from hereditary melanoma kindreds.

Melanoma research - 1 Feb 2001

Shannon J A, Kefford R F, Mann G J

Abstract excerpt

Ultraviolet-B (UV-B) triggers a cascade of events involving cell cycle control genes leading ultimately to DNA repair or apoptosis. The hypothesis examined here is that the genetic abnormality predisposing to melanoma affects the ability of the cell to respond appropriately to UV-B, so favouring mutagenesis. Epstein-Barr virus-transformed lymphoblastoid cell lines from hereditary melanoma kindreds were irradiated...

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Identifiers

PMID: 11254110
DOI: 10.1097/00008390-200102000-00001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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