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Article

Location and Clonal Analysis of Stem Cells and Their Differentiated Progeny in the Human Ocular Surface

17 May 1999

Abstract excerpt

We have analyzed the proliferative and differentiation potential of human ocular keratinocytes. Holoclones, meroclones, and paraclones, previously identified in skin, constitute also the proliferative compartment of the ocular epithelium. Ocular holoclones have the expected properties of stem cells, while transient amplifying cells have variable proliferative potential. Corneal stem cells are segregated in the...

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PMID: 10330405
DOI: 10.1083/jcb.145.4.769

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